TY - JOUR T1 - Violence and Schizophrenia: Clozapine as a Specific Antiaggressive Agent JF - Journal of the American Academy of Psychiatry and the Law Online JO - J Am Acad Psychiatry Law SP - 607 LP - 611 VL - 23 IS - 4 AU - Peter Buckley AU - James Bartell AU - Karl Donenwirth AU - Shin Lee AU - Frank Torigoe AU - S. Charles Schulz Y1 - 1995/12/01 UR - http://jaapl.org/content/23/4/607.abstract N2 - Pharmacological management of persistent aggression in patients with schizophrenia is a difficult clinical dilemma. Clozapine has been shown to be an effective agent in this regard. This study sought to compare the symptomatic response on the Brief Psychiatric Rating Scale (BPRS) between hostile schizophrenic patients and patients without aggression. While dramatic improvements were evident in aggression, both groups were indistinguishable with respect to BPRS response. These results suggest that clozapine may have a selective antiaggressive effect. ER -