RT Journal Article SR Electronic T1 Violence and Schizophrenia: Clozapine as a Specific Antiaggressive Agent JF Journal of the American Academy of Psychiatry and the Law Online JO J Am Acad Psychiatry Law FD American Academy of Psychiatry and the Law SP 607 OP 611 VO 23 IS 4 A1 Peter Buckley A1 James Bartell A1 Karl Donenwirth A1 Shin Lee A1 Frank Torigoe A1 S. Charles Schulz YR 1995 UL http://jaapl.org/content/23/4/607.abstract AB Pharmacological management of persistent aggression in patients with schizophrenia is a difficult clinical dilemma. Clozapine has been shown to be an effective agent in this regard. This study sought to compare the symptomatic response on the Brief Psychiatric Rating Scale (BPRS) between hostile schizophrenic patients and patients without aggression. While dramatic improvements were evident in aggression, both groups were indistinguishable with respect to BPRS response. These results suggest that clozapine may have a selective antiaggressive effect.