PT - JOURNAL ARTICLE AU - Elias Ghossoub AU - Susan Minchin AU - Davinder Hayreh AU - William J. Newman TI - Long-Acting Injectable versus Oral Antipsychotics for Restoration of Competency to Stand Trial AID - 10.29158/JAAPL.003866-19 DP - 2019 Dec 01 TA - Journal of the American Academy of Psychiatry and the Law Online PG - 440--447 VI - 47 IP - 4 4099 - http://jaapl.org/content/47/4/440.short 4100 - http://jaapl.org/content/47/4/440.full SO - J Am Acad Psychiatry Law2019 Dec 01; 47 AB - Treatment with antipsychotics is a mainstay of trial competency restoration, particularly given that most defendants deemed incompetent to stand trial have psychotic illnesses. We explored the association between competency restoration and antipsychotic type in a retrospective sample of defendants diagnosed with psychotic disorders and deemed incompetent to stand trial. Using regression models, we calculated the odds ratio of being competent to stand trial, adjusting for relevant confounders. We found that the use of long-acting injectable antipsychotics was not significantly associated with increased odds of restoration of trial competency. Our results highlight the need for larger, longitudinal studies to further explore the efficacy and tolerability of long-acting injectable drugs compared with oral antipsychotics. Future research will help develop treatment guidelines within the setting of trial competency restoration.