Disruptive mood dysregulation disorder: a new diagnostic approach to chronic irritability in youth

Am J Psychiatry. 2014 Sep;171(9):918-24. doi: 10.1176/appi.ajp.2014.13101301.

Abstract

Disruptive mood dysregulation disorder (DMDD), a newcomer to psychiatric nosology, addresses the need for improved classification and treatment of children exhibiting chronic nonepisodic irritability and severe temper outbursts. In recent years, many of these children have been diagnosed with bipolar disorder, despite the lack of distinct mood episodes. This diagnostic practice has raised concerns, in part because of the escalating prescription of atypical antipsychotics. This article provides an overview of the limited literature on DMDD, including its history and relevant studies of assessment and treatment. A case study is included to illustrate key points, including diagnostic issues that clinicians may encounter when considering a diagnosis of DMDD.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anticonvulsants / therapeutic use
  • Antimanic Agents / therapeutic use
  • Antipsychotic Agents* / classification
  • Antipsychotic Agents* / therapeutic use
  • Attention Deficit and Disruptive Behavior Disorders* / diagnosis
  • Attention Deficit and Disruptive Behavior Disorders* / drug therapy
  • Attention Deficit and Disruptive Behavior Disorders* / psychology
  • Child
  • Child Behavior / psychology
  • Diagnosis, Differential
  • Diagnostic and Statistical Manual of Mental Disorders
  • Family Therapy / methods
  • Humans
  • Irritable Mood / drug effects*
  • Mood Disorders* / diagnosis
  • Mood Disorders* / drug therapy
  • Mood Disorders* / psychology
  • Psychiatric Status Rating Scales
  • Randomized Controlled Trials as Topic
  • Treatment Outcome

Substances

  • Anticonvulsants
  • Antimanic Agents
  • Antipsychotic Agents