Abstract
The authors report a significant increase in dyscontrol in patients with borderline personality disorder who were taking alprazolam during a double-blind, placebo-controlled crossover study. They suggest that caution be used in prescribing alprazolam to patients with similar histories.
MeSH terms
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Adult
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Alprazolam
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Ambulatory Care
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Anti-Anxiety Agents / adverse effects*
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Benzodiazepines / adverse effects*
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Benzodiazepines / therapeutic use
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Borderline Personality Disorder / drug therapy*
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Borderline Personality Disorder / psychology
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Clinical Trials as Topic
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Double-Blind Method
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Female
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Humans
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Impulsive Behavior / chemically induced
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Personality Disorders / drug therapy*
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Placebos
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Self Mutilation / chemically induced
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Suicide, Attempted / psychology
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Violence
Substances
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Anti-Anxiety Agents
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Placebos
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Benzodiazepines
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Alprazolam