User profiles for A. A. Gopal

Angelica A Gopal

Research Fellow, Massachusetts General Hospital/ Harvard Medical School
Verified email at mgh.harvard.edu
Cited by 211

Migration-induced cell shattering due to DOCK8 deficiency causes a type 2–biased helper T cell response

C Schneider, C Shen, AA Gopal, T Douglas… - Nature …, 2020 - nature.com
Mutations that impact immune cell migration and result in immune deficiency illustrate the
importance of cell movement in host defense. In humans, loss-of-function mutations in DOCK8, …

CYRI/FAM49B negatively regulates RAC1-driven cytoskeletal remodelling and protects against bacterial infection

KE Yuki, H Marei, E Fiskin, MM Eva, AA Gopal… - Nature …, 2019 - nature.com
Salmonella presents a global public health concern. Central to Salmonella pathogenicity is
an ability to subvert host defences through strategically targeting host proteins implicated in …

[PDF][PDF] Physician-assisted suicide: Considering the evidence, existential distress, and an emerging role for psychiatry

AA Gopal - Journal of the American Academy of Psychiatry and …, 2015 - researchgate.net
Physician-assisted suicide (PAS) is one of the most provocative topics facing society today.
Given the great responsibility conferred on physicians by recent laws allowing PAS, a careful …

[HTML][HTML] Plant-derived virus-like particle vaccines drive cross-presentation of influenza A hemagglutinin peptides by human monocyte-derived macrophages

AI Makarkov, M Golizeh, E Ruiz-Lancheros, AA Gopal… - NPJ vaccines, 2019 - nature.com
… ) were fully overlapping with up to three unique AA sequences identified in our study. Since
… peptides identified were longer than the 8–10 AA thought to be optimal for MHC I loading. It …

Recent advances in nonlinear microscopy: Deep insights and polarized revelations

AA Gopal, A Kazarine, JM Dubach… - The international journal …, 2021 - Elsevier
Nonlinear microscopy is a technique that utilizes nonlinear interactions between light and
matter to image fluorescence and scattering phenomena in biological tissues. Very high peak …

[PDF][PDF] Netrin-1-regulated distribution of UNC5B and DCC in live cells revealed by TICCS

AA Gopal, B Rappaz, V Rouger, IB Martyn… - Biophysical …, 2016 - cell.com
… of the cross correlation function normalized by the amplitudes of the autocorrelation functions,
and the ratio of the effective areas is defined by the focal spots of the two lasers (Ab > Aa

Malaria detection by third-harmonic generation image scanning cytometry

A Kazarine, F Baakdah, AA Gopal, W Oyibo… - Analytical …, 2019 - ACS Publications
Despite global efforts aimed at its elimination, malaria is still a significant health concern in
many countries across the world. The disease is caused by blood-borne parasites, …

Covalent bond orders and atomic anisotropies from iterated stockholder atoms

RJ Wheatley, AA Gopal - Physical Chemistry Chemical Physics, 2012 - pubs.rsc.org
… This sum includes b = a, and the quantity C aa is the number of ‘unshared’ electrons of
atom a. If the atoms are stockholder atoms, defined using eqn (1), then eqn (5) can be re-…

Multimodal virtual histology of rabbit vocal folds by nonlinear microscopy and nano computed tomography

A Kazarine, K Kolosova, AA Gopal, H Wang… - Biomedical optics …, 2019 - opg.optica.org
Human vocal folds (VFs) possess a unique anatomical structure and mechanical properties
for human communication. However, VFs are prone to scarring as a consequence of overuse…

Nonlinear microscopy of common histological stains reveals third harmonic generation harmonophores

A Kazarine, AA Gopal, PW Wiseman - Analyst, 2019 - pubs.rsc.org
Since its invention over a hundred years ago, histological analysis using coloured dye
staining remains the gold standard for histopathology. While these stains provide critical …