Existing pathophysiological models of schizophrenia are limited in their ability to account for
all the clinical dimensions of the disorder. The purpose of this article is to describe a …

Defining treatment resistance among schizophrenia patients is problematic since most
patients experience persistent morbidity over the course of their illness and full remissions are …

Pathophysiological processes that underlie the profound neuropsychiatric disturbances in
schizophrenia are poorly understood. However, the clinical course of the disease, and a …

This pilot study was undertaken to estimate the acute antipsychotic effect size and side
effect propensity of risperidone and olanzapine in the pediatric population, in comparison to …

A first episode of psychosis is a traumatic experience for patients and families. At the time of
initial evaluation, the differential diagnosis should include a broad range of neurological, …

A number of consistent clinical observations provide direction for the hypothesis that pathological
sensitization of neuronal systems may be an important factor for relapse or the onset of …

The synaptosomal-associated protein of 25kDa (SNAP-25) is an essential component of the
core complex that mediates presynaptic vesicle trafficking. Thus, SNAP-25 is directly …

This letter presents a report answering the question: Are the negative symptoms of
schizophrenia consistent with an autistic spectrum illness? The purposes of this report are:(1) to …

To the Editor: The relatively recent introduction of the newer atypical antipsychotic
medications—risperidone, olanzapine, quetiapine—has resulted in a shift in the prescribing …

Objective: Emergency Departments (ED) are overburdened with patients experiencing
acute mental health crises. Pre-hospital transport by Emergency Medical Services (EMS) to …