User profiles for Helen C. Kales

Helen Kales

University of California Davis
Verified email at ucdavis.edu
Cited by 23157

Dementia prevention, intervention, and care: 2020 report of the Lancet Commission

…, A Dias, N Fox, LN Gitlin, R Howard, HC Kales… - The Lancet, 2020 - thelancet.com
The number of older people, including those living with dementia, is rising, as younger age
mortality declines. However, the age-specific incidence of dementia has fallen in many …

Dementia prevention, intervention, and care

…, C Cooper, N Fox, LN Gitlin, R Howard, HC Kales… - The lancet, 2017 - thelancet.com
Executive summary Acting now on dementia prevention, intervention, and care will vastly
improve living and dying for individuals with dementia and their families, and in doing so …

Assessment and management of behavioral and psychological symptoms of dementia

HC Kales, LN Gitlin, CG Lyketsos - Bmj, 2015 - bmj.com
Behavioral and psychological symptoms of dementia include agitation, depression, apathy,
repetitive questioning, psychosis, aggression, sleep problems, wandering, and a variety of …

Antipsychotics, other psychotropics, and the risk of death in patients with dementia: number needed to harm

…, J Kavanagh, LS Schneider, HC Kales - JAMA …, 2015 - jamanetwork.com
Importance Antipsychotic medications are associated with increased mortality in older adults
with dementia, yet their absolute effect on risk relative to no treatment or an alternative …

Management of neuropsychiatric symptoms of dementia in clinical settings: recommendations from a multidisciplinary expert panel

HC Kales, LN Gitlin, CG Lyketsos… - Journal of the …, 2014 - Wiley Online Library
C enter and C enter for I nnovative C are in A ging sponsored and convened a multidisciplinary
expert panel in D etroit, M ichigan, in fall 2011 with three objectives: to define critical …

Nonpharmacologic management of behavioral symptoms in dementia

LN Gitlin, HC Kales, CG Lyketsos - Jama, 2012 - jamanetwork.com
Behavioral symptoms such as repetitive speech, wandering, and sleep disturbances are a
core clinical feature of Alzheimer disease and related dementias. If untreated, these behaviors …

Risk of mortality among individual antipsychotics in patients with dementia

HC Kales, HM Kim, K Zivin… - American Journal of …, 2012 - Am Psychiatric Assoc
Objective: The use of antipsychotics to treat the behavioral symptoms of dementia is associated
with greater mortality. The authors examined the mortality risk of individual agents to …

Mortality risk in patients with dementia treated with antipsychotics versus other psychiatric medications

HC Kales, M Valenstein, HM Kim… - American Journal of …, 2007 - Am Psychiatric Assoc
Objective: Mortality rates in the year following new antipsychotic medication starts for
neuropsychiatric symptoms of dementia were compared with rates after starts of other psychiatric …

[HTML][HTML] Psychosis in Alzheimer disease—mechanisms, genetics and therapeutic opportunities

…, HC Kales, CG Lyketsos, RA Sweet, C Ballard - Nature Reviews …, 2022 - nature.com
Psychosis is a common and distressing symptom in people with Alzheimer disease, and few
safe and effective treatments are available. However, new approaches to symptom …

Management of behavioral and psychological symptoms in people with Alzheimer's disease: an international Delphi consensus

HC Kales, CG Lyketsos, EM Miller… - International …, 2019 - cambridge.org
Objectives:Behavioral and psychological symptoms of dementia (BPSD) are nearly universal
in dementia, a condition occurring in more than 40 million people worldwide. BPSD …