This practice review focuses on the challenges of conducting sensitive and accurate
assessments of the relative risk for suicide attempts and completed suicides. Suicide and suicide …

The ENCyclopedia Of DNA Elements (ENCODE) Project aims to identify all functional elements
in the human genome sequence. The pilot phase of the Project is focused on a specified …

We report the generation and analysis of functional data from multiple, diverse experiments
performed on a targeted 1% of the human genome as part of the pilot phase of the ENCODE …

The extent to which cells in normal tissues accumulate mutations throughout life is poorly
understood. Some mutant cells expand into clones that can be detected by genome …

This review aims to clarify the underlying risk of arrhythmia associated with the use of
macrolides and fluoroquinolones antibiotics. Torsades de pointes (TdP) is a rare potential side …

We generated high-resolution maps of histone H3 lysine 9/14 acetylation (H3ac), histone
H4 lysine 5/8/12/16 acetylation (H4ac), and histone H3 at lysine 4 mono-, di-, and …

Recent editions of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5; American
Psychiatric Association, 2013) conceptualize personality disorders (PDs) as categorical …

In an era of tremendous medical advancements, it is important to characterise and address
inequities in the provision of health care and in outcomes. There is a large body of evidence …

Human epithelial tissues accumulate cancer-driver mutations with age 1 , 2 , 3 , 4 , 5 , 6 , 7 ,
8 – 9 , yet tumour formation remains rare. The positive selection of these mutations suggests …

… Later, these protocols were independently scored by Fowler or Piers for research purposes.
Because the protocols from this sample were initially used for clinical purposes, this sample …