Approximately 70 percent of the mutations in cystic fibrosis patients correspond to a specific
deletion of three base pairs, which results in the loss of a phenylalanine residue at amino …

Stromal interacting molecule 1 (STIM1), reported to be an endoplasmic reticulum (ER) Ca 2+
sensor controlling store-operated Ca 2+ entry, redistributes from a diffuse ER localization …

The study of executive function within a developmental framework has proven integral to the
advancement of knowledge concerning the acquisition and decline of higher skill processes…

The activation of store-operated Ca 2+ entry by Ca 2+ store depletion has long been
hypothesized to occur via local interactions of the endoplasmic reticulum (ER) and plasma …

Little is known about presynaptic assembly during central nervous system synaptogenesis.
Here we used time-lapse fluorescence imaging, immunocytochemistry and electron …

We are performing whole-genome sequencing of families with autism spectrum disorder (ASD)
to build a resource (MSSNG) for subcategorizing the phenotypes and underlying genetic …

The analyzing power in inclusive charged pion production has been measured using the 200
GeV Fermilab polarized proton beam. A striking dependence in x F is observed in which A …

Changes in arterial wall composition and function underlie all forms of vascular disease.
The fundamental structural and functional unit of the aortic wall is the medial lamellar unit (MLU)…

We assembled a semi-automated reconstruction of L2/3 mouse primary visual cortex from ∼250
× 140 × 90 μm 3 of electron microscopic images, including pyramidal and non-…

… Janet Buchanan’s work on this article was supported by funds from the University of Toronto
McLaughlin Centre. Lonnie Zwaigenbaum holds the Stollery Children’s Hospital Foundation …