Psoriasis, a papulosquamous skin disease, was originally thought of as a disorder primarily
of epidermal keratinocytes, but is now recognised as one of the commonest immune-…

To gain further insight into the genetic architecture of psoriasis, we conducted a meta-analysis
of 3 genome-wide association studies (GWAS) and 2 independent data sets genotyped …

(WTCCC2) consortia is provided in the Supplementary Note online. Author Contributions FC,
ADB, CEMG, J. Kere., A. Reis, JNB and RCT oversaw cohort collection for both the …

Environmental stimuli responsible for inducing cutaneous inflammation include contact
allergens and ultraviolet light. We postulate that these diverse stimuli trigger a cutaneous …

Psoriasis is now classified as an immune-mediated inflammatory disease (IMID) of the skin.
It is being recognized that patients with various IMIDs, including psoriasis, are at higher risk …

… Karvonen/Barker/Rantanen … The calcium-antagonist diltiazem, the antimycotics
ketoconazole and itraconazole, the macrolide antibiotics (with the exception of azithromycin) …

We simultaneously investigated the genetic landscape of ankylosing spondylitis, Crohn's
disease, psoriasis, primary sclerosing cholangitis and ulcerative colitis to investigate pleiotropy …

Psoriasis is a common chronic inflammatory disorder of the skin. To further understand the
pathogenesis of psoriasis we have chosen to investigate the molecular genetic basis of the …

Generalized pustular psoriasis (GPP) is a rare and yet potentially lethal clinical variant of
psoriasis, characterized by the formation of sterile cutaneous pustules, neutrophilia, fever and …

Psoriasis is an inflammatory skin disorder that is inherited as a multifactorial trait. Genetic
analyses have repeatedly identified a primary disease susceptibility locus lying within the …