Many research designs require the assessment of inter-rater reliability (IRR) to demonstrate
consistency among observational ratings provided by multiple coders. However, many …

Background Mobile apps for mental health have the potential to overcome access barriers
to mental health care, but there is little information on whether patients use the interventions …

Background The rate of participant attrition in alcohol clinical trials is often substantial and
can cause significant issues with regard to the handling of missing data in statistical analyses …

Background Alcohol use disorder (AUD) is a highly prevalent public health problem
associated with considerable individual and societal costs. Abstinence from alcohol is the most …

Motivational interviewing (MI) is an efficacious treatment for substance use disorders and
other problem behaviors. Studies on MI fidelity and mechanisms of change typically use …

Background and Aims Recovery from alcohol use disorder (AUD) is often narrowly defined
by abstinence from alcohol and improvements in functioning (eg mental health, social …

Background Abstinence and no heavy drinking days are currently the only Food and Drug
Administration–approved end points in clinical trials for alcohol use disorder ( AUD ). Many …

The vitamin K oxidoreductase (VKOR) reduces vitamin K to support the carboxylation and
consequent activation of vitamin K-dependent proteins, but the mechanism of reduction is …

A characteristic feature of classic pseudoxanthoma elasticum (PXE), an autosomal recessive
disorder caused by mutations in the ABCC6 gene, is aberrant mineralization of connective …

Background We sought to understand alcohol behavior change as a process over time by
identifying patterns of relapse and remission after outpatient treatment and evaluating how …