OBJECTIVE: To determine the utility of serum miRNAs as biomarkers for epithelial ovarian
cancer. METHODS: Twenty-eight patients with histologically confirmed epithelial ovarian …

OBJECTIVE.: To compare the clinical behavior and outcomes of low- and high-grade
endometrial stromal sarcomas (LGESS and HGESS), respectively. METHODS.: Patients with …

Resistance to platinum-based chemotherapy is the major barrier to treating epithelial ovarian
cancer. To improve patient outcomes, it is critical to identify the underlying mechanisms …

Purpose To determine whether the addition of bevacizumab to paclitaxel and carboplatin for
the primary treatment of advanced ovarian cancer can be cost effective. Methods A cost-…

OBJECTIVE: Lynch syndrome is a heritable, cancer susceptibility syndrome. This study
aims to review current and emerging trends in the identification of Lynch syndrome in the …

OBJECTIVE: We sought to determine a microRNA (miRNA) profile of surgically staged
endometrial cancers. STUDY DESIGN: RNA was extracted from archival primary endometrial …

Background: Recurrent gynecologic cancers are often difficult to manage without significant
morbidity. We conducted a phase II study to assess the safety and the efficacy of ablative …

OBJECTIVE: Cervical and vaginal cancers have virally-mediated or mutated defects in DNA
damage repair responses, making these cancers sensible targets for ribonucleotide …

OBJECTIVE: To correlate survival and surgical-pathologic factors with DNA mismatch repair
status in patients with endometrial cancer. METHODS: Specimens from 336 patients with …

This study characterizes a highly recurrent, disease-specific PP2A PPP2R1A mutation as a
driver of endometrial carcinoma and a target for novel therapeutic development. See related …