Metagenomic analyses can provide extensive information on the structure, composition,
and predicted gene functions of diverse environmental microbial assemblages. Each …

Using both sequence- and function-based metagenomic approaches, multiple antibiotic
resistance determinants were identified within metagenomic libraries constructed from DNA …

Copy number variants (CNVs) and intragenic rearrangements of the NRXN1 (neurexin 1)
gene are associated with a wide spectrum of developmental and neuropsychiatric disorders, …

Differences in smoke constituent exposure by ethnicity and menthol preference and
differences in decisional balance and habit strength by stage of change, ethnicity, and menthol …

Plastic pollution is a modern tragedy of the commons, with hundreds of species affected by
society's waste. Birds in particular mistake plastic for prey, and millions of wild birds carry …

Pre-mRNA splicing is a highly coordinated process. While its dysregulation has been linked
to neurological deficits, our understanding of the underlying molecular and cellular …

X-linked SCID (SCID-X1) is amenable to correction by gene therapy using conventional
gammaretroviral vectors. Here, we describe the occurrence of clonal T cell acute lymphoblastic …

Background X-linked severe combined immunodeficiency (SCID-X1) is caused by mutations
in the common cytokine-receptor γchain(γc), resulting in disruption of development of T …

Genetic defects in the purine salvage enzyme adenosine deaminase (ADA) lead to severe
combined immunodeficiency (SCID) with profound depletion of T, B, and natural killer cell …

X-linked severe combined immunodeficiency (SCID-X1) is caused by mutations in the
common cytokine receptor γ chain. These mutations classically lead to complete absence of …