User profiles for M. E. Hirschtritt

Matthew E. Hirschtritt, MD, MPH

Clinical Fellow, Forensic Psychiatry; University of California, San Francisco
Verified email at ucsf.edu
Cited by 4672

Obsessive-compulsive disorder: advances in diagnosis and treatment

ME Hirschtritt, MH Bloch, CA Mathews - Jama, 2017 - jamanetwork.com
Importance Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder associated
with significant impairment and a lifetime prevalence of 1% to 3%; however, it is often …

Lifetime prevalence, age of risk, and genetic relationships of comorbid psychiatric disorders in Tourette syndrome

ME Hirschtritt, PC Lee, DL Pauls, Y Dion… - JAMA …, 2015 - jamanetwork.com
… Author Contributions: Drs Hirschtritt and Lee contributed equally to this study, as did Drs
Scharf and Mathews. Drs Hirschtritt and Lee had full access to all the data in the study and take …

Digital technologies in psychiatry: present and future

ME Hirschtritt, TR Insel - Focus, 2018 - Am Psychiatric Assoc
Hirschtritt is with the Weill Institute for Neurosciences and Department of Psychiatry, University
Hirschtritt serves as a consultant to Carbon Health. Dr. Insel is an employee of Mindstrong …

Interrogating the genetic determinants of Tourette's syndrome and other tic disorders through genome-wide association studies

…, L Osiecki, SM Darrow, ME Hirschtritt… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: Tourette’s syndrome is polygenic and highly heritable. Genome-wide association
study (GWAS) approaches are useful for interrogating the genetic architecture and …

[PDF][PDF] Rare copy number variants in NRXN1 and CNTN6 increase risk for Tourette syndrome

…, S Chouinard, S Darrow, E Greenberg, ME Hirschtritt… - Neuron, 2017 - cell.com
Tourette syndrome (TS) is a model neuropsychiatric disorder thought to arise from abnormal
development and/or maintenance of cortico-striato-thalamo-cortical circuits. TS is highly …

Addressing problems with alcohol and other substances among older adults during the COVID-19 pandemic

DD Satre, ME Hirschtritt… - … American Journal of …, 2020 - Am Assoc Geria Psych
Older adults are more vulnerable than younger adults to the effects of substance use, including
the exacerbation of chronic medical and mental health conditions. These concerns are …

[PDF][PDF] De novo coding variants are strongly associated with Tourette disorder

…, Y Dion, NB Freimer, MA Grados, ME Hirschtritt… - Neuron, 2017 - cell.com
Whole-exome sequencing (WES) and de novo variant detection have proven a powerful
approach to gene discovery in complex neurodevelopmental disorders. We have completed …

[PDF][PDF] De novo sequence and copy number variants are strongly associated with tourette disorder and implicate cell polarity in pathogenesis

…, Y Dion, NB Freimer, MA Grados, ME Hirschtritt… - Cell reports, 2018 - cell.com
We previously established the contribution of de novo damaging sequence variants to
Tourette disorder (TD) through whole-exome sequencing of 511 trios. Here, we sequence an …

Balancing the risks and benefits of benzodiazepines

ME Hirschtritt, M Olfson, K Kroenke - Jama, 2021 - jamanetwork.com
… Conflict of Interest Disclosures: Dr Hirschtritt reported being supported in part by a contract
from the California Mental Health Services Oversight and Accountability Commission (outside …

Agreement between youth self-report and biospecimen-confirmed substance use: a systematic review

JB Folk, ME Hirschtritt, QD McCrary… - Substance use & …, 2022 - Taylor & Francis
Context Biospecimen analysis may enhance confidence in the accuracy of self-reported
substance use among adolescents and transitional age youth (TAY). Associations between …