The purpose of this study was to evaluate the effectiveness of several new approaches designed
to enhance the activity of fluorouracil (5-FU) in the management of advanced colorectal …

DNA damage causes cell-cycle delay before S phase, during replication and before mitosis.
This involves a number of highly conserved proteins that sense DNA damage and signal the …

This article describes challenges and successes seen in the first four years of efforts the
state of Connecticut has made to reorient its behavioral health system to promoting recovery. …

… that emission increases nearly linearly for energy densities below 0.1 mJ cm -2 but sublinearly
at higher excitation levels, with an emission efficiency at 6 mJ cm -2 only ∼25% of that …

Single-walled carbon nanotubes (SWNTs) have been solubilized in water by non-covalently
associating them with linear polymers, most successfully with polyvinyl pyrrolidone (PVP) …

One‐hundred‐ninety‐four eligible and evaluable patients with histologically confirmed locally
unresectable adenocarcinoma of the pancreas were randomly assigned to therapy with …

Background The combination of radiation therapy and chemotherapy with fluorouracil plus
semustine after surgery has been established as an effective approach to decreasing the risk …

… O’Connell graduated with a BS in biochemistry and molecular biology from the University
of California in 1998 and developed an interest in the emerging field of nanotechnology. He …

Purpose This phase III clinical trial evaluated the impact on disease-free survival (DFS) of
adding oxaliplatin to bolus weekly fluorouracil (FU) combined with leucovorin as surgical …

PURPOSE The goal of this study was to determine the efficacy of intensive-course fluorouracil
(5FU) plus low-dose leucovorin given for 6 months following potentially curative resection …