Proteolysis-targeting chimeras (PROTACs) are an emerging drug modality that may offer
new opportunities to circumvent some of the limitations associated with traditional small-…

The Eukaryotic Linear Motif (ELM) resource ( http://elm.eu.org ) is a manually curated
database of short linear motifs (SLiMs). In this update, we present the latest additions to this …

Understanding the causes and consequences of variation in the rate of recombination is
essential since this parameter is considered to affect levels of genetic variability, the efficacy of …

Topical structure analysis (TSA), a text-based approach to the study of topic in discourse,
has been useful in identifying text-based features of coherence. It has also been used to …

Rationale: Arterial inflammation manifested as atherosclerosis is the leading cause of mortality
worldwide. Genome-wide association studies have identified a prominent role of HDAC (…

Rare-earth phosphors with tunable optical properties are used in display panels and fluorescent
lamps and have potential applications in lasers and bioimaging. Here, nonaggregated …

Poor aqueous solubility and dissolution of drug candidates drive key decisions on lead
series optimization during drug discovery, on formulation optimization, and clinical studies …

Endocrine-disrupting chemicals (EDCs) are a broad class of molecules present in our
environment that are suspected to cause adverse effects in the endocrine system by interfering …

Silica-coated and uncoated, Tb-doped (1–5 at % Tb) Y 2 O 3 green nanophosphors were
made, for the first time, in a single step by flame aerosol technology with controlled crystal …

Appearance and performance enhancing drug (APED) use includes the use of a range of
pharmacologically distinct substances and concurrent investment in outward appearance or …