Leukocyte infiltration of cerebral vessels in cocaine-associated vasculopathy suggests that
cocaine may enhance leukocyte migration. We have investigated cocaine's effects on …

Background Chemokine receptors on leukocytes play a key role in inflammation and HIV-1
infection. Chemokine receptors on endothelia may serve an important role in HIV-1 tissue …

Normal brain development requires a series of highly complex and interrelated steps. This
process presents many opportunities for errors to occur, which could result in developmental …

Previous studies have demonstrated that stromal cell-derived factor 1 (SDF-1) is crucial for
early dentate development; however, the mouse mutants for this chemokine and its only …

Posttraumatic stress disorder (PTSD) has been offered as a basis for criminal defenses,
including insanity, unconsciousness, self-defense, diminished capacity, and sentencing …

Introduction Intracapsular hip fractures (ICHF) are a common cause of morbidity and mortality
and pose a great economic burden on the health care systems. Appropriate surgical …

The effects of cocaine infusion (40 mg) on interferon-γ (IFN-γ) and interleukin-10 (IL-10)
cytokine secretion were examined in 15 cocaine-dependent subjects. Pre- and postcocaine …

Background The pathogenesis of HIV-1-related cardiomyopathy is poorly understood, but
HIV-1 has been detected in cardiomyocytes. Whether HIV-1 penetrates into the myocardium …

Mossy cells are the major class of excitatory neurons in the dentate hilus. Although mossy
cells are involved in a range of physiological and pathological conditions, very little is known …

Conclusions HIV-1 binding to receptors on brain endothelia, possibly CCR3 and CXCR4,
may initiate a cascade of effects that culminate in increased transcellular penetration of the …