Pain Physician: March/April 2011; 14: 123-143 124 www. painphysicianjournal. com patterns
of drug use and compliance so as to direct the type and conduct of treatment that can and …

Oxycodone, a semisynthetic opioid analgesic, is widely used in clinical practice. Oxycodone
was first synthesized from thebaine in Germany in 1917. 1 For decades, researchers have …

The epoxyeicosatrienoic acids (EETs) are products of cytochrome P450 epoxygenases that
have vasodilatory properties similar to that of endothelium-derived hyperpolarizing factor. …

Background: The introduction of intrathecal opioid administration for intractable chronic non-malignant
pain and cancer pain is considered as one of the most important breakthroughs in …

The authors stated there was good evidence for transforaminal epidural injections for chronic
low back and lower extremity pain caused by disc herniation with radiculitis; the evidence …

This is the critical fallacy that we think makes the online rating of doctors lack validity. In the
online rating of physicians, patient satisfaction is used as a metric similar to customer …

102 American Journal of Medical Quality 31 (2) system, participating patients and clinicians),
patient selection (eg, inclusion/exclusion criteria, enrichment strategies), patient …

U-47700 (3, 4-dichloro-N-[2-(dimethylamino) cyclohexyl]-N-methylbenzamide) is a novel
compound with opioid properties, developed by Upjohn in the 1970s and derived from the …

Background: Spinal analgesia, mediated by opioid receptors, requires only a fraction of the
opioid dose that is needed systemically. By infusing a small amount of opioid into the …

Background: The introduction of newly formulated extended release (ER) morphine with
sequestered naltrexone (Embeda) has provided another treatment option for moderate to …