Acute phase proteins as promising biomarkers: Perspectives and limitations for human and veterinary medicine

W Schrödl, R Büchler, S Wendler… - PROTEOMICS …, 2016 - Wiley Online Library
Acute phase proteins (APPs) are highly conserved plasma proteins that are increasingly
secreted by the liver in response to a variety of injuries, independently of their location and …

Macrophages in bone fracture healing: their essential role in endochondral ossification

…, T El Khassawna, A Serra, A Dienelt, S Wendler… - Bone, 2018 - Elsevier
… Bones were loaded to failure in torsion at 0.5 /s with an axial preload of 0.3 N (ElectroForce
3200 test system, BOSE, USA). Ultimate torque and torsional stiffness were measured from …

Autonomous rhythmic activity in glioma networks drives brain tumour growth

…, M Ratliff, JM Messmer, Y Yang, E Reyhan, S Wendler… - Nature, 2023 - nature.com
… We next investigated how glioblastoma cells translate the network’s rhythmic Ca 2+
oscillations into biological information. Multiple key intracellular signalling pathways have Ca 2+ …

Neurofilament markers for ALS correlate with extent of upper and lower motor neuron disease

…, B Stubendorff, B Gille, P Muckova, S Wendler… - Neurology, 2017 - AAN Enterprises
Objective: To determine the diagnostic performance and prognostic value of phosphorylated
neurofilament heavy chain (pNfH) and neurofilament light chain (NfL) in CSF as possible …

[HTML][HTML] Clinically Approved Drugs Inhibit the Staphylococcus aureus Multidrug NorA Efflux Pump and Reduce Biofilm Formation

…, M Klinger-Strobel, JA Bohnert, S Wendler… - Frontiers in …, 2019 - frontiersin.org
… The problem is exacerbated by increasing antibiotic resistance among S. aureus clinical …
This ability of S. aureus is not only limited to planktonic bacteria but also extends to biofilms. …

[HTML][HTML] Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy

…, C Schumacher, SL Boos, AS Daniel, S Wendler… - Nature …, 2020 - nature.com
… Statistical analyses for multiple comparisons are by one-way or two-way ANOVA with
Tukey’s, Dunnett’s or Fisher’s LSD post hoc multiple comparison test as indicated in the figure …

[HTML][HTML] T lymphocytes influence the mineralization process of bone

…, C Schlundt, I Könnecke, D Malhan, S Wendler… - Frontiers in …, 2017 - frontiersin.org
… are involved in fracture healing using Movat’s pentachrome staining. The Movat’s pentachrome
is a combination of alcian blue solution, Weigert’s iron hematoxylin, brilliant crocein acid …

[HTML][HTML] Experience in the adaptive immunity impacts bone homeostasis, remodeling, and healing

…, C Schlundt, D Wulsten, FA Sass, S Wendler… - Frontiers in …, 2019 - frontiersin.org
Bone formation as well as bone healing capacity is known to be impaired in the elderly.
Although bone formation is outpaced by bone resorption in aged individuals, we hereby present …

Age‐dependent decline in fin regenerative capacity in the short‐lived fish Nothobranchius furzeri

S Wendler, N Hartmann, B Hoppe, C Englert - Aging Cell, 2015 - Wiley Online Library
… the fraction of cells in S phase and G2/M … in S phase was higher than that in the
nonregenerating fins (0 dpa). In accordance with the EdU staining, the highest percentage of cells in …

Assent in paediatric research: theoretical and practical considerations

DS Wendler - Journal of medical ethics, 2006 - jme.bmj.com
Guidelines around the world require children to provide assent for their participation in most
research studies. Yet, little further guidance is provided on how review committees should …