PT  - JOURNAL ARTICLE
AU  - Buckley, Peter
AU  - Bartell, James
AU  - Donenwirth, Karl
AU  - Lee, Shin
AU  - Torigoe, Frank
AU  - Schulz, S. Charles
TI  - Violence and Schizophrenia: Clozapine as a Specific Antiaggressive Agent
DP  - 1995 Dec 01
TA  - Journal of the American Academy of Psychiatry and the Law Online
PG  - 607--611
VI  - 23
IP  - 4
4099  - http://jaapl.org/content/23/4/607.short
4100  - http://jaapl.org/content/23/4/607.full
SO  - J Am Acad Psychiatry Law1995 Dec 01; 23
AB  - Pharmacological management of persistent aggression in patients with schizophrenia is a difficult clinical dilemma. Clozapine has been shown to be an effective agent in this regard. This study sought to compare the symptomatic response on the Brief Psychiatric Rating Scale (BPRS) between hostile schizophrenic patients and patients without aggression. While dramatic improvements were evident in aggression, both groups were indistinguishable with respect to BPRS response. These results suggest that clozapine may have a selective antiaggressive effect.