RT Journal Article
SR Electronic
T1 Violence and Schizophrenia: Clozapine as a Specific Antiaggressive Agent
JF Journal of the American Academy of Psychiatry and the Law Online
JO J Am Acad Psychiatry Law
FD American Academy of Psychiatry and the Law
SP 607
OP 611
VO 23
IS 4
A1 Buckley, Peter
A1 Bartell, James
A1 Donenwirth, Karl
A1 Lee, Shin
A1 Torigoe, Frank
A1 Schulz, S. Charles
YR 1995
UL http://jaapl.org/content/23/4/607.abstract
AB Pharmacological management of persistent aggression in patients with schizophrenia is a difficult clinical dilemma. Clozapine has been shown to be an effective agent in this regard. This study sought to compare the symptomatic response on the Brief Psychiatric Rating Scale (BPRS) between hostile schizophrenic patients and patients without aggression. While dramatic improvements were evident in aggression, both groups were indistinguishable with respect to BPRS response. These results suggest that clozapine may have a selective antiaggressive effect.