Length of Stay (LOS) in Days before Starting Clozapine, on Clozapine Trial and after Clozapine Trial Discontinued
| Hospital Days | Discharged on Clozapine | Clozapine Discontinued Prior to Discharge | ||||
|---|---|---|---|---|---|---|
| Restored (n = 69) | Not Restored (n = 104) | Restored (n = 7) | Not Restored (n = 11) | Test Stat | p | |
| Before starting clozapine | 227.19 ± 171.60 | 330.03 ± 197.22 | 353.86 ± 260.14 | 413.64 ± 215.52 | F = 5.632 (df = 3) | .001a |
| On clozapine | 174.43 ± 142.29 | 239.66 ± 113.77 | 99.86 ± 83.01 | 149.27 ± 122.37 | F = 6.464 (df = 3) | .000b |
| After clozapine discontinued | – | – | 93.43 ± 69.74 | 195.55 ± 164.88 | F = 2.371 (df = 1) | .143c |
| Total Hospital (Length of Stay) | 397.25 ± 230.87 | 567.04 ± 209.75 | 545.43 ± 250.16 | 673.36 ± 163.77 | F = 10.75 (df = 3) | .000d |
Note. Statistical significance was determined by using analysis of variance and the post hoc Tukey’s multiple comparisons test. Cloz/Rest = patients maintained on clozapine until discharge and restored to competency; ClozDC/NonRest = patients discontinued from clozapine and not restored to competency; Cloz/NonRest = patients maintained on clozapine and not restored to competency.
↵a There were statistically significant between-group differences in length of stay (LOS) before the start of the clozapine trial, F(3, 187) = 5.632, p = .001): Cloz/Rest (227.19 ± 171.60 days) was shorter than ClozDC/NonRest (413.64 ± 215.52 days) and Cloz/NonRest (330.03 ± 197.22 days).
↵b Among those who were discharged on clozapine there were statistically significant differences in the time on clozapine, F(3, 187) = 6.464, p = .000): Cloz/NonRest (239.66 ± 113.77 days) and Cloz/Rest (174.43 ± 142.29 days).
↵c Among those who had clozapine discontinued before hospital discharge, there were no statistically significant differences between groups in the length of stay (LOS) after clozapine was discontinued.
↵d There were statistically significant between group differences in total LOS (F [3, 187] = 10.75, p = .000): Cloz/Rest (397.25 ± 230.87 days) was shorter than ClozDC/NonRest (673.36 ± 163.77 days) and Cloz/NonRest (567.04 ± 209.75 days).