Journal of the American Academy of Child & Adolescent Psychiatry
New researchExamination of Disruptive Behavior Outcomes and Moderation in a Randomized Psychotherapy Trial for Mood Disorders
Section snippets
Sample
Secondary analyses examined the MF-PEP RCT (National Institute of Mental Health grant R01MH061512), which included 165 children with mood disorders and their families.29 Participants were recruited from Midwestern rural and urban settings through a referral network of mental health professionals, presentations to professional and community-based groups, and media feature stories about the study. Children had to be 8 to 11 years old and have a mood disorder and IQ higher than 70.
The sample size
Baseline Data
Study recruitment and assessments were conducted from 2001 through 2005. Figure 1 presents the participant flow. Analyses included all participants for whom 12-month follow-up data were available, except for Pearson correlations, which used the intent-to-treat cohort. By 12-month follow-up, 18 families had dropped out of the IMM + TAU group and 26 had dropped out of the WLC + TAU group. Families not completing treatment (n = 49 who did not complete ≥6 sessions) did not differ from completers on
Discussion
Children with mood disorders commonly present with comorbid DBDs. Little is known about the impact of psychosocial mood interventions on DBD symptoms and the impact of DBDs on mood symptom treatment response. This secondary analysis of MF-PEP, an efficacious psychoeducational treatment for children with mood disorders, showed that disruptive behaviors were associated with more severe mood symptoms and worse global functioning at baseline. Between-group analyses examining outcomes of disruptive
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Cited by (24)
Outcome Findings and Issues in Psychotherapy With Children and Adolescents: Internalizing Disorders
2022, Comprehensive Clinical Psychology, Second EditionPsychoeducational and Skill-building Interventions for Emotion Dysregulation
2021, Child and Adolescent Psychiatric Clinics of North AmericaCitation Excerpt :PEP is an example of the class of well-established interventions, family psychoeducation plus skill building for youth with mood disorders who experience considerable emotion dysregulation. The novel findings presented in this article support the efficacy of MF-PEP for reducing irritability and aggressive/disruptive behavior, whereas the summarized prior findings show benefits of MF-PEP for overall mood symptom severity18 and disruptive behavior.17 IF-PEP, especially when combined with omega-3 supplementation, also has been shown to reduce mood symptoms,23 disruptive behavior,24 and executive functioning deficits.25
How can adolescent aggression be reduced? A multi-level meta-analysis
2020, Clinical Psychology ReviewComorbid disorders as moderators of response to family interventions among adolescents with bipolar disorder
2019, Journal of Affective DisordersCitation Excerpt :DBDs (ODD and CD) were examined as one group due to the small sample of participants with CD (see Table 1). However, based on research indicating differential effects of multifamily psychoeducational psychotherapy (MF-PEP) on ODD and CD symptoms in youth with mood disorders (Boylan et al., 2013), we conducted secondary analyses examining ODD only. Analyses of variance (ANOVA) were used to examine differences across comorbidity groups (anxiety, ADHD, DBDs) and treatment groups (FFT versus EC) in the percentage of time with and without depressive or (hypo)manic symptoms over the 2-year study.
The role of family interventions in bipolar disorder: A systematic review
2016, Clinical Psychology ReviewCitation Excerpt :In adolescents with BD and comorbid substance used disorder, preliminary findings of a pilot single-arm open treatment study on family focused treatment (Goldstein et al., 2014) indicated that the intervention might be effective in treating mood symptoms but the reduction in substance use was modest. Positive findings have been obtained with multifamily psychoeducation for youth with comorbid mood and disruptive behavior disorders (Boylan et al., 2013). Nevertheless, despite the differences between studies, the findings of this review support the benefits of adjunctive family intervention in BD.
Family-Based Interventions for Childhood Mood Disorders
2015, Child and Adolescent Psychiatric Clinics of North AmericaCitation Excerpt :In a pilot RCT, MF-PEP demonstrated greater improvements in family interactions and knowledge of mood disorders compared with WLC.41–43 In addition, comorbid behavior and anxiety disorders did not impede improvement in mood,44,45 and behavioral symptoms improved with treatment.44 These findings suggests that MF-PEP is efficacious in treating mood disorders and improving service engagement.
Dr. Boylan served as the statistical expert for this research.
Disclosure: Dr. Fristad has received royalties for a treatment manual published by Guilford Press and multifamily psychoeducational psychotherapy (MF-PEP) workbooks (http://www.moodychildtherapy.com). She has also received funding from the National Institute of Mental Health. Dr. Boylan and Ms. MacPherson report no biomedical financial interests or potential conflicts of interest.