Protocols for the use of cyproterone, medroxyprogesterone, and leuprolide in the treatment of paraphilia

Can J Psychiatry. 2000 Aug;45(6):559-63. doi: 10.1177/070674370004500608.

Abstract

Objective: To propose a protocol for minimizing medical complications associated with the use of cyproterone, medroxyprogesterone, and depot leuprolide to treat paraphilia.

Method: Review of the relevant literature.

Results: Certain patient populations should not be treated with these medications, and medical complications associated with each can be detected early and avoided.

Conclusions: For each drug, a series of screening tests prior to use and scheduled testing during use can minimize potential medical complications.

Publication types

  • Review

MeSH terms

  • Administration, Oral
  • Androgen Antagonists / administration & dosage*
  • Androgen Antagonists / adverse effects
  • Cyproterone Acetate / administration & dosage*
  • Cyproterone Acetate / adverse effects
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Humans
  • Injections, Intramuscular
  • Leuprolide / administration & dosage*
  • Leuprolide / adverse effects
  • Male
  • Medroxyprogesterone / administration & dosage*
  • Medroxyprogesterone / adverse effects
  • Paraphilic Disorders / diagnosis
  • Paraphilic Disorders / drug therapy*
  • Paraphilic Disorders / psychology

Substances

  • Androgen Antagonists
  • Cyproterone Acetate
  • Leuprolide
  • Medroxyprogesterone