Leuprolide acetate for exhibitionism in Huntington's disease

Mov Disord. 1994 May;9(3):353-7. doi: 10.1002/mds.870090317.

Abstract

We treated a patient with Huntington's disease and exhibitionism using leuprolide acetate (Lupron Depot, TAP Pharmaceuticals), a gonadotropin-releasing hormone agonist. The result was elimination of his deviant sexual behavior with few side effects. This regimen may be a safe and effective pharmacological treatment of the paraphilias. The occurrence of paraphilias in basal ganglia disorders is reviewed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Delayed-Action Preparations
  • Dementia / drug therapy*
  • Dementia / genetics
  • Dementia / psychology
  • Exhibitionism / drug therapy*
  • Exhibitionism / psychology
  • Humans
  • Huntington Disease / drug therapy*
  • Huntington Disease / genetics
  • Huntington Disease / psychology
  • Injections, Intramuscular
  • Leuprolide / adverse effects
  • Leuprolide / therapeutic use*
  • Male
  • Neurologic Examination / drug effects

Substances

  • Delayed-Action Preparations
  • Leuprolide