Abstract
We treated a patient with Huntington's disease and exhibitionism using leuprolide acetate (Lupron Depot, TAP Pharmaceuticals), a gonadotropin-releasing hormone agonist. The result was elimination of his deviant sexual behavior with few side effects. This regimen may be a safe and effective pharmacological treatment of the paraphilias. The occurrence of paraphilias in basal ganglia disorders is reviewed.
MeSH terms
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Adult
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Delayed-Action Preparations
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Dementia / drug therapy*
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Dementia / genetics
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Dementia / psychology
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Exhibitionism / drug therapy*
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Exhibitionism / psychology
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Humans
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Huntington Disease / drug therapy*
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Huntington Disease / genetics
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Huntington Disease / psychology
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Injections, Intramuscular
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Leuprolide / adverse effects
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Leuprolide / therapeutic use*
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Male
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Neurologic Examination / drug effects
Substances
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Delayed-Action Preparations
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Leuprolide