A cleavage method which minimizes side reactions following Fmoc solid phase peptide synthesis

DS King, CG FIELDS, GB FIELDS - International journal of …, 1990 - Wiley Online Library
The success of solid phase peptide synthesis utilizing 9‐fluorenylmethoxycarbonyl (Fmoc)
amino acids is often limited by deleterious side reactions which occur during TFA peptide‐…

[HTML][HTML] Design and characterization of a fluorogenic substrate selectively hydrolyzed by stromelysin 1 (matrix metalloproteinase-3).

H Nagase, CG Fields, GB Fields - Journal of Biological Chemistry, 1994 - Elsevier
Members of the matrix metalloproteinase (MMP) family have been implicated in disease
states such as arthritis, periodontal disease, and tumor cell invasion and metastasis. …

Sequence dependence of aspartimide formation during 9-fluorenylmethoxycarbonyl solid-phase peptide synthesis

JL Lauer, CG Fields, GB Fields - Letters in peptide science, 1995 - Springer
We have examined the sequence dependence of aspartimide formation during Fmoc-based
solid-phase synthesis of the peptide Val-Lys-Asp-X-Tyr-Ile. The extent of aspartimide …

Celecoxib or naproxen treatment does not benefit depressive symptoms in persons age 70 and older: findings from a randomized controlled trial

C Fields, L Drye, V Vaidya, C Lyketsos… - The American Journal of …, 2012 - Elsevier
Background Several lines of evidence suggest that inflammatory mechanisms may be involved
in the severity and progression of depression. One pathway implicated is the production …

Solvation effects in solid-phase peptide synthesis

GB Fields, CG Fields - Journal of the American Chemical Society, 1991 - ACS Publications
The success of solid-phase peptide synthesis is highly dependent on the accessibility of the
growing resin-bound peptide chain to reagents. To maximize this accessibility, the …

[PDF][PDF] A study of geriatric forensic evaluees: who are the violent elderly?

CF Lewis, C Fields, E Rainey - Journal of the American Academy of …, 2006 - Citeseer
The objective of this study was to examine a sample (n 99) of elderly forensic evaluees to
describe the psychiatric, medical, legal, and demographic characteristics of the sample and to …

Solid‐phase synthesis and stability of triple‐helical peptides incorporating native collagen sequences

CG Fields, CM Lovdahl, AJ Miles… - Biopolymers …, 1993 - Wiley Online Library
A generally applicable solid‐phase methodology has been developed for the synthesis of
triple‐helical polypeptides incorporating native collagen sequences. Three nascent peptide …

Minimization of tryptophan alkylation following 9-fluorenylmethoxycarbonyl solid-phase peptide synthesis

CG Fields, GB Fields - Tetrahedron Letters, 1993 - Elsevier
We have examined Pmc and Pbf side-chain protection of Arg and Boc side-chain protection
of Trp in an attempt to minimize side-chain protecting group “scavenger” use following Fmoc-…

Utilization of glucose oxidase for extending the shelf‐life of fish

CE Field, LF Pivarnik, SM Barnett… - Journal of Food …, 1986 - Wiley Online Library
The preservative benefits of the enzymic glucose oxidase/catalase system were measured
in refrigerated, fresh, whole winter flounder (Pseudopleuronectes americanus Waldbaum) …

A survey of sessional faculty in Ontario publicly-funded universities

CC Field, GA Jones - 2016 - tspace.library.utoronto.ca
Within the past decade, the unprecedented growth in non-tenure/tenure track faculty has led
to speculation as to the learning environment and learning outcomes for students. Both …