User profiles for Helen Zhou

Juan Helen Zhou

- Verified email at nus.edu.sg - Cited by 11603

Helen Zhou

- Verified email at andrew.cmu.edu - Cited by 209

[HTML][HTML] Multiple amino acid residues confer temperature sensitivity to human influenza virus vaccine strains (FluMist) derived from cold-adapted A/Ann Arbor/6/60

H Jin, B Lu, H Zhou, C Ma, J Zhao, C Yang, G Kemble… - Virology, 2003 - Elsevier
FluMist influenza A vaccine strains contain the PB1, PB2, PA, NP, M, and NS gene
segments of ca A/AA/6/60, the master donor virus–A strain. These gene segments impart the …

Glycosylation at 158N of the hemagglutinin protein and receptor binding specificity synergistically affect the antigenicity and immunogenicity of a live attenuated H5N1 …

W Wang, B Lu, H Zhou, AL Suguitan Jr… - Journal of …, 2010 - Am Soc Microbiol
A live attenuated influenza A/Vietnam/1203/2004 (H5N1) vaccine virus (VN04 ca) has
receptor binding specificity to α2,3-linked sialosides (α2,3SAL), and a single dose induces a …

Recombinant respiratory syncytial viruses with deletions in the NS1, NS2, SH, and M2-2 genes are attenuated in vitro and in vivo

H Jin, H Zhou, X Cheng, R Tang, M Munoz, N Nguyen - Virology, 2000 - Elsevier
Respiratory syncytial virus (RSV) encodes several proteins that lack well-defined functions;
these include NS1, NS2, SH, and M2-2. Previous work has demonstrated that NS2, SH, and …

Generation of live attenuated novel influenza virus A/California/7/09 (H1N1) vaccines with high yield in embryonated chicken eggs

Z Chen, W Wang, H Zhou, AL Suguitan Jr… - Journal of …, 2010 - Am Soc Microbiol
Several live attenuated influenza virus A/California/7/09 (H1N1) (CA09) candidate vaccine
variants that possess the hemagglutinin (HA) and neuraminidase (NA) gene segments from …

One prophage WO gene rescues cytoplasmic incompatibility in Drosophila melanogaster

…, J On, EM Layton, H Zhou… - Proceedings of the …, 2018 - National Acad Sciences
Wolbachia are maternally inherited, intracellular bacteria at the forefront of vector control efforts
to curb arbovirus transmission. In international field trials, the cytoplasmic incompatibility (…

Improvement of influenza A/Fujian/411/02 (H3N2) virus growth in embryonated chicken eggs by balancing the hemagglutinin and neuraminidase activities, using …

B Lu, H Zhou, D Ye, G Kemble, H Jin - Journal of virology, 2005 - Am Soc Microbiol
The H3N2 influenza A/Fujian/411/02-like virus strains that circulated during the 2003-2004
influenza season caused influenza epidemics. Most of the A/Fujian/411/02 virus lineages did …

Mammalian two-hybrid system: a complementary approach to the yeast two-hybrid system

Y Luo, A Batalao, H Zhou, L Zhu - Biotechniques, 1997 - Taylor & Francis
Here we demonstrate the use of a mammalian two-hybrid system to study protein-protein
interactions. Like the yeast two-hybrid system, this is a genetic, in vivo assay based on the …

Imparting temperature sensitivity and attenuation in ferrets to A/Puerto Rico/8/34 influenza virus by transferring the genetic signature for temperature sensitivity from …

H Jin, H Zhou, B Lu, G Kemble - Journal of virology, 2004 - Am Soc Microbiol
The four temperature-sensitive (ts) loci identified in the PB1 and PB2 gene segments of cold-adapted
A/Ann Arbor/6/60 influenza virus, the master donor virus for influenza A virus (MDV-…

A decision algorithm to promote outpatient antimicrobial stewardship for uncomplicated urinary tract infection

S Kanjilal, M Oberst, S Boominathan, H Zhou… - Science translational …, 2020 - science.org
Antibiotic resistance is a major cause of treatment failure and leads to increased use of
broad-spectrum agents, which begets further resistance. This vicious cycle is epitomized by …

[HTML][HTML] Two residues in the hemagglutinin of A/Fujian/411/02-like influenza viruses are responsible for antigenic drift from A/Panama/2007/99

H Jin, H Zhou, H Liu, W Chan, L Adhikary, K Mahmood… - Virology, 2005 - Elsevier
The H3N2 vaccine strain (A/Panama/2007/99) for the 2003–2004 influenza season did not
antigenically match the circulating A/Fujian/411/02-like H3N2 viruses and had reduced …