User profiles for Jaya L. Padmanabhan
 | Jaya PadmanabhanTakeda Pharmaceuticals Verified email at partners.org Cited by 1412 |
Brain stimulation and brain lesions converge on common causal circuits in neuropsychiatric disease
Damage to specific brain circuits can cause specific neuropsychiatric symptoms. Therapeutic
stimulation to these same circuits may modulate these symptoms. To determine whether …
stimulation to these same circuits may modulate these symptoms. To determine whether …
A human depression circuit derived from focal brain lesions
… Author links open overlay panel Jaya L. Padmanabhan a b c , Danielle Cooke b , Juho
Joutsa b e f , Shan H. Siddiqi a b c d g , Michael Ferguson b , R. Ryan Darby h , Louis Soussand …
Joutsa b e f , Shan H. Siddiqi a b c d g , Michael Ferguson b , R. Ryan Darby h , Louis Soussand …
Correlations between brain structure and symptom dimensions of psychosis in schizophrenia, schizoaffective, and psychotic bipolar I disorders
Introduction: Structural alterations may correlate with symptom severity in psychotic disorders,
but the existing literature on this issue is heterogeneous. In addition, it is not known how …
but the existing literature on this issue is heterogeneous. In addition, it is not known how …
[HTML][HTML] Recent advances in understanding schizophrenia
Schizophrenia is a highly disabling disorder whose causes remain to be better understood,
and treatments have to be improved. However, several recent advances have been made in …
and treatments have to be improved. However, several recent advances have been made in …
The “polyenviromic risk score”: aggregating environmental risk factors predicts conversion to psychosis in familial high-risk subjects
Background Young relatives of individuals with schizophrenia (ie youth at familial high-risk,
FHR) are at increased risk of developing psychotic disorders, and show higher rates of …
FHR) are at increased risk of developing psychotic disorders, and show higher rates of …
[HTML][HTML] Polygenic risk for schizophrenia and measured domains of cognition in individuals with psychosis and controls
Psychotic disorders including schizophrenia are commonly accompanied by cognitive deficits.
Recent studies have reported negative genetic correlations between schizophrenia and …
Recent studies have reported negative genetic correlations between schizophrenia and …
Dysplasticity, metaplasticity, and schizophrenia: implications for risk, illness, and novel interventions
…, UM Mehta, JL Padmanabhan… - Development and …, 2015 - cambridge.org
In this paper, we review the history of the concept of neuroplasticity as it relates to the
understanding of neuropsychiatric disorders, using schizophrenia as a case in point. We briefly …
understanding of neuropsychiatric disorders, using schizophrenia as a case in point. We briefly …
Impulsivity across the psychosis spectrum: correlates of cortical volume, suicidal history, and social and global function
Patients with psychotic disorders appear to exhibit greater impulsivity-related behaviors
relative to healthy controls. However, the neural underpinning of this impulsivity remains …
relative to healthy controls. However, the neural underpinning of this impulsivity remains …
Polygenic risk for type 2 diabetes mellitus among individuals with psychosis and their relatives
… Author links open overlay panel Jaya L. Padmanabhan a b , Pranav Nanda c , Neeraj
Tandon a d , Suraj S. Mothi a , Nicolas Bolo a , Steven McCarroll e f g , Brett A. Clementz k …
Tandon a d , Suraj S. Mothi a , Nicolas Bolo a , Steven McCarroll e f g , Brett A. Clementz k …
A proposed solution to integrating cognitive-affective neuroscience and neuropsychiatry in psychiatry residency training: the time is now
Despite increasing recognition of the importance of a strong neuroscience and neuropsychiatry
education in the training of psychiatry residents, achieving this competency has proven …
education in the training of psychiatry residents, achieving this competency has proven …