User profiles for Matthew W. Motley

Matthew Warren Motley

NYU School of Medicine
Verified email at nyumc.org
Cited by 114

Imaging intratumoral convection: pressure-dependent enhancement in chemotherapeutic delivery to solid tumors

TPF Gade, IM Buchanan, MW Motley, Y Mazaheri… - Clinical Cancer …, 2009 - AACR
Purpose: Low–molecular weight (LMW) chemotherapeutics are believed to reach tumors
through diffusion across capillary beds as well as membrane transporters. Unexpectedly, the …

[HTML][HTML] Imaging of alkaline phosphatase activity in bone tissue

TP Gade, MW Motley, BJ Beattie, R Bhakta… - PLoS …, 2011 - journals.plos.org
The purpose of this study was to develop a paradigm for quantitative molecular imaging of
bone cell activity. We hypothesized the feasibility of non-invasive imaging of the osteoblast …

Enzyme homologues have distinct reaction paths through their transition states

I Zoi, MW Motley, D Antoniou… - The Journal of …, 2015 - ACS Publications
Recent studies of the bacterial enzymes EcMTAN and VcMTAN showed that they have
different binding affinities for the same transition state analogue. This was surprising given the …

Conformational freedom in tight binding enzymatic transition-state analogues

MW Motley, VL Schramm… - The Journal of Physical …, 2013 - ACS Publications
Transition-state analogues of bacterial 5′-methylthioadenosine/S-adenosylhomocysteine
nucleosidases (MTANs) disrupt quorum-sensing pathways in Escherichia coli and Vibrio …

[BOOK][B] Freedom in Transition: Computational Studies of Escherichia coli MTAN and Vibro cholerae MTAN

MW Motley - 2013 - search.proquest.com
Transition state analogue inhibitors of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine
nucleosidase (EcMTAN) and Vibrio cholerae 5'-methylthioadenosine/S-…

[PDF][PDF] Rare variants in MME, encoding metalloprotease neprilysin, are linked to late-onset autosomal-dominant axonal polyneuropathies

…, MB Harms, W Motley, MM Reilly, W Renner… - The American Journal of …, 2016 - cell.com
Axonal polyneuropathies are a frequent cause of progressive disability in the elderly. Common
etiologies comprise diabetes mellitus, paraproteinaemia, and inflammatory disorders, but …

[BOOK][B] The American Abraham: James Fenimore Cooper and the Frontier Patriarch

W Motley - 1987 - books.google.com
In this book Warren Motley offers an original interpretation of James Fenimore Cooper's
career. Whereas most studies of Cooper have centered on the figure of the Leatherstocking-that …

Isoform-specific loss of dystonin causes hereditary motor and sensory neuropathy

WW Motley, S Züchner, SS Scherer - Neurology: Genetics, 2020 - AAN Enterprises
… They also thank Matt C. Danzi for help analyzing the primary sequencing data. … WW Motley
is a full-time employee of Third Rock Ventures. S. Züchner and SS Scherer report no relevant …

Electrostatic oscillations near the ion cyclotron frequency

N D'Angelo, RW Motley - Physics of Fluids (New York), 1962 - osti.gov
Measurements of ion wave instabilities in plasma in which the electron drift velocity is a few%
of the electron thermal speed and ion and electron temperatures are about equal are …

[CITATION][C] Must an Attorney Investigate and Consider a Diminished Capacity Defense?

MW Motley, T Botello - JOURNAL OF …, 2020 - … & LAW ONE REGENCY DR, PO …