User profiles for R Franklin

Richard C Franklin

Professor, Public Health - Injury Prevention and Safety Promotion, James Cook University
Verified email at jcu.edu.au
Cited by 110968

[HTML][HTML] Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance

…, C Evangelisti, AM Martelli, RA Franklin - … et Biophysica Acta (BBA …, 2007 - Elsevier
Growth factors and mitogens use the Ras/Raf/MEK/ERK signaling cascade to transmit
signals from their receptors to regulate gene expression and prevent apoptosis. Some …

Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.

…, PM Navolanic, WL Blalock, RA Franklin… - Leukemia …, 2003 - search.ebscohost.com
The Ras/Raf/Mitogen-activated protein kinase/ERK kinase (MEK)/extracellular-signal-regulated
kinase (ERK) cascade couples signals from cell surface receptors to transcription factors…

Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance

…, PM Navolanic, DM Terrian, RA Franklin… - Advances in enzyme …, 2006 - Elsevier
The Ras/Raf/MEK/ERK and PI3K/PTEN/AKT signaling cascades play critical roles in the
transmission of signals from growth factor receptors to regulate gene expression and prevent …

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

…, MH Forouzanfar, FGR Fowkes, R Franklin… - The lancet, 2012 - thelancet.com
Background Reliable and timely information on the leading causes of death in populations,
and how these are changing, is a crucial input into health policy debates. In the Global …

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

…, K Foreman, MH Forouzanfar, FGR Fowkes, R Franklin… - The lancet, 2012 - thelancet.com
Background Non-fatal health outcomes from diseases and injuries are a crucial consideration
in the promotion and monitoring of individual and population health. The Global Burden of …

The global burden of cancer 2013

…, R Dellavalle, R Weintraub, R Lucas, R Hay… - JAMA …, 2015 - jamanetwork.com
Importance Cancer is among the leading causes of death worldwide. Current estimates of
cancer burden in individual countries and regions are necessary to inform local cancer control …

Case study research: Foundations and methodological orientations

H Harrison, M Birks, R Franklin… - Forum qualitative …, 2017 - qualitative-research.net
Over the last forty years, case study research has undergone substantial methodological
development. This evolution has resulted in a pragmatic, flexible research approach, capable of …

The global burden of injury: incidence, mortality, disability-adjusted life years and time trends from the Global Burden of Disease study 2013

…, F Farzadfar, VL Feigin, RC Franklin… - Injury …, 2016 - injuryprevention.bmj.com
Background The Global Burden of Diseases (GBD), Injuries, and Risk Factors study used
the disability-adjusted life year (DALY) to quantify the burden of diseases, injuries, and risk …

[HTML][HTML] Hearing loss prevalence and years lived with disability, 1990–2019: findings from the Global Burden of Disease Study 2019

…, M Ekholuenetale, I Filip, F Fischer, RC Franklin… - The Lancet, 2021 - thelancet.com
Background Hearing loss affects access to spoken language, which can affect cognition and
development, and can negatively affect social wellbeing. We present updated estimates …

Reactive oxygen species-induced activation of the MAP kinase signaling pathways

…, MM LaHair, RA Franklin - Antioxidants & redox …, 2006 - liebertpub.com
An abundance of scientific literature exists demonstrating that oxidative stress influences
the MAPK signaling pathways. This review summarizes these findings for the ERK, JNK, p38, …