Article Figures & Data
Figures
- Figure 1.
Distributions of the difference in assigned restrictive housing (RH) days among patients before (pre) and after (post) clozapine treatment for 0–3, 3–6, 6–9, and 9–12 months. The X indicates the mean reduction; the shaded area represents the interquartile range, and whiskers represent minimum and maximum values excluding outliers (i.e., values > 1.5 times the interquartile range below the 25th percentile or above the 75th percentile; outliers not shown). Median values are typically represented by a horizontal line within the interquartile range, but in these plots, the median overlaps with the 75th percentile line (i.e., has a value of zero).*The test to detect a pre-/post difference was statistically significant using the Wilcoxon-Signed Rank Test (P < 0.05).
- Figure 2.
Distribution of quarterly assigned restrictive housing (RH) days among patients during 12 months of continuous clozapine treatment The X indicates the mean reduction; the shaded area represents the interquartile range, and whiskers represent minimum and maximum values excluding outliers (i.e., values > 1.5 times the interquartile range below the 25th percentile or above the 75th percentile; outliers not shown). Median values are typically represented by a horizontal line within the interquartile range, but in some instances the median overlaps with the 25th percentile line (i.e., has a value of zero).
Tables
- Table 1
Demographic and Clinical Characteristics of Patients Receiving Clozapine for ≥ 3 Months or < 3 Months
Characteristics Clozapine ≥ 3 Months Clozapine < 3 Months P Subjects, n 59 25 Sex 1.0 Male 49 (83.1) 21 (84.0) Female 10 (16.9) 4 (16.0) Race 0.24 White 32 (54.2) 9 (36.0) Black 21 (35.6) 14 (56.0) Other 6 (10.2) 2 (8.0) Age, years 0.27 18–25 7 (11.9) 3 (12.0) 26–40 38 (64.4) 12 (48.0) > 40 14 (23.7) 10 (40.0) Gang affiliation 19 (32.2) 6 (10.2) 0.60 Primary psychiatric diagnosis 0.34 Psychotic disorder 23 (39.0) 13 (52.0) Personality disorder 36 (61.0) 12 (48.0) History of self-injurious behavior or suicide attempt 57 (96.6) 19 (76.0) 0.008 Substance use disorder 57 (96.6) 21 (84.0) 0.06 Prior medication trials in prison Antipsychotic 3.8 ± 2.0 3.4 ± 2.2 Mood stabilizer 1.8 ± 1.1 1.2 ± 1.2 Intellectual disability 3 (5.1) 2 (8.0) 0.63 Seizure disorder 12 (20.3) 2 (8.0) 0.21 Data are presented as n (%) or mean ± SD.
- Table 2
Distribution of Assigned Restrictive Housing Days Pre- and Post- Clozapine Treatment
Duration of Clozapine Treatment 0–3 Months 3–6 Months 6–9 Months 9–12 Months Pre- Post- Difference Pre- Post- Difference Pre- Post- Difference Pre- Post- Difference Maximum 855 870 300 1,195 240 70 585 105 40 1,090 120 80 75% percentile 70 0 0 52.5 0 0 75 0 0 112.5 10 0 Median 0 0 0 0 0 0 0 0 0 10 0 0 25% percentile 0 0 −60 0 0 −52.5 0 0 −60 0 0 −97.5 Minimum 0 0 −360 0 0 −1,195 0 0 −510 0 0 −1,000 P* .0005 .0013 .0006 .01 Subjects, n 59 44 33 24 ↵* Determined with the Wilcoxon signed rank test.
